ever notice how the sci-fi shows always have some equivalent of the 'uncharted territories'?
ever notice how the good guys always end up dukin it out with the bad guys there like an old west frontier?
Science tries to describe without influencing the subject. Experiments, once set up, must work independently from theories, the map must be causally downstream from the territory. This Must becomes an expectation and creates a blind spot. But only the most well-behaved fields really work this way: Sociology and Psychology that deal with social realities struggle with this, especially. For many areas of interest, the map is carved into the territory by its usage, a herbivore trail both formed by and forming the territory. Language, world views, even our memories are such maps, changing whenever they're used.