Although this is a game where gender and sexuality are already drastically impacted by cybernetic implants. Enough metal and gender's moot.
Also major themes of sex work in the game. Multiple missions involving bloodbathes at brothels, beating up sleazy pimps, POV sexual encounters - one time even assuming the perspective of Keanu Reeves' character.
The protagonists sexual fluidity is cupped within the potential of your dialogue choices. Also pretty sure you can approach sex workers in the manner of approaching a vendor. Next time I play I'll try it, report back.
It does feel like everyone's hard 'n perky for everyone in this game. It really is a red-bull-sponsored hyperlibidinal take on cyberpunk, rather than the more melancholic and nihilistic take I tend to think of.